This easy meatloaf recipe combines simple ingredients with a flavorful glaze, creating a juicy and tender loaf that will become a family favorite. Perfect for a weeknight dinner or a comforting meal to serve to guests!

Ingredients

2/3 cup panko breadcrumbs
1/4 cup whole milk
2 pounds ground beef (see note)
2 large eggs
4 cloves garlic, minced
1 teaspoon onion powder
1 teaspoon Italian seasoning
1 teaspoon salt
Freshly ground black pepper, to taste
1/4 cup fresh parsley, chopped
2 tablespoons ketchup

For the Glaze:

1/4 cup ketchup
1/4 cup BBQ sauce (see note)
2 tablespoons brown sugar

Instructions

1. Preheat the Oven:

Set your oven to 375°F and position the rack in the middle of the oven.

2. Prepare the Meatloaf:

In a large bowl, combine the panko breadcrumbs and milk. Stir to mix and let it sit for a few minutes to absorb.
Add the ground beef, eggs, garlic, onion powder, Italian seasoning, salt, pepper, parsley, and ketchup to the bowl with the soaked breadcrumbs. Mix everything together using your hands, but avoid overworking the meat to keep the loaf tender.

3. Shape the Meatloaf:

Transfer the meat mixture into a 9×5 loaf pan lined with parchment paper (make sure some paper hangs over the edges for easy removal later). Press the mixture gently into the pan and shape the top into a loaf.

4. Bake the Meatloaf:

Place the pan in the oven and bake for 40 minutes. To prevent any drips, place the loaf pan on a baking sheet.

5. Make the Glaze:

While the meatloaf bakes, mix together the glaze ingredients (ketchup, BBQ sauce, and brown sugar) in a small bowl until well combined.

6. Add the Glaze:

After 40 minutes of baking, remove the meatloaf from the oven. Spoon the glaze over the top of the meatloaf, spreading it evenly. Return the pan to the oven and bake for another 15 minutes, or until the internal temperature reaches 155°F.

7. Rest and Slice:

Let the meatloaf rest for 10-15 minutes after removing it from the oven. This helps the juices redistribute and makes it easier to slice. The meatloaf will continue cooking and reach a safe 160°F as it rests.
Once rested, lift the meatloaf out of the pan using the parchment paper and transfer it to a plate. Slice and serve.

Why You’ll Love This Recipe

Flavorful and Juicy: The combination of ground beef, seasonings, and a delicious glaze keeps this meatloaf moist and full of flavor.
Simple Ingredients: With everyday pantry staples, this meatloaf is easy to make and requires minimal preparation.
Family-Friendly: A comforting dish that appeals to everyone, making it perfect for busy weeknights or Sunday dinners.

Tips

Don’t Overwork the Meat: When mixing the meatloaf, try not to overwork the mixture. Overmixing can make the meatloaf tough.
Resting Time is Key: Allow the meatloaf to rest after baking so it stays juicy and is easier to slice.
Use Lean Beef: Opt for lean ground beef to reduce excess fat, but don’t use extra-lean beef as it may result in a drier meatloaf.
Catch Drips: Place the loaf pan on a baking sheet to catch any drips from the meatloaf and glaze.

Variations and Substitutions

Ground Meat: You can swap the ground beef for ground turkey, chicken, or pork for a lighter alternative.
Breadcrumbs: If you don’t have panko, regular breadcrumbs can be used as a substitute.
Spices: Experiment with different seasonings, such as paprika, garlic powder, or a bit of cayenne pepper for some heat.
Glaze Variations: Swap the BBQ sauce with mustard, or use a mixture of brown sugar and balsamic vinegar for a tangy twist.

FAQs

Q: Can I make meatloaf ahead of time?
A: Yes! You can prepare the meatloaf mixture and refrigerate it for up to 24 hours before baking. Add the glaze just before the final baking step.

Q: Can I freeze meatloaf?
A: Absolutely! After baking, let the meatloaf cool, then wrap it tightly in plastic wrap and foil. Freeze for up to 3 months. To reheat, thaw in the fridge and bake until warmed through.

Q: How do I know when the meatloaf is done?
A: Use a meat thermometer to check the internal temperature. It should reach 160°F for safe consumption.

Serving and Suggestions

Side Dishes: Serve with mashed potatoes, roasted vegetables, or a fresh salad for a complete meal.
Bread Pairing: A side of garlic bread or dinner rolls is perfect for soaking up the flavorful glaze.
Leftover Ideas: Use leftovers to make meatloaf sandwiches or chop it up for a hearty pasta sauce.